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In vitro comparative study demonstrates improved pH and hypotonic stress recovery in polyolefin-stored platelets at five days, indicating feasible prolonged storage.
Summary. Platelet concentrates have been prepared in standard PVC (PL- 146) packs and polyolefin (PL-732) packs. Comparison of pH and hypotonic stress of the platelet concentrates has shown that significantly improved values are obtained after storage of the concentrates at 22|MoC in PL-732 packs for 5 days than after storage for 3 days in PL-146 packs. There was no significant difference under conditions of the test between vertical and horizontal agitation of the concentrates. Since both pH and hypotonic stress recovery have shown a relationship to post-transfusion recovery and viability, evidence is presented to support the 5-day storage period of concentrates prepared and stored in PL-732 packs.
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Gunson et al. (2008) studied this question.
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