Key result
Normothermia during aortic valve surgery did not influence early neurological, renal, or cardiac complications compared to hypothermia, though hypothermia required less catecholamine (p=0.00001).
Why the study?
Does systemic perfusion in normothermia improve early clinical outcomes in patients undergoing aortic valve surgery compared to moderate hypothermia?
Cohort (n=323)
Does systemic perfusion in normothermia improve early clinical outcomes in patients undergoing aortic valve surgery compared to moderate hypothermia?
Cardiopulmonary bypass temperature (normothermia vs moderate hypothermia) does not significantly influence early clinical outcomes after aortic valve surgery.
Suggests no early outcome advantage to normothermia in aortic valve surgery; leaves open optimal temperature strategy pending randomized trials.
The purpose of this study was to examine the effects of systemic perfusion temperature on the clinical outcome after aortic valve surgery. In this study, we examined 323 patients who underwent aortic valve surgery between January 1994 and April 1996. Forty-six patients were perfused in moderate hypothermia (28 degrees C) and 277 patients in normothermia. Age and sex distribution of the patients were similar. There were no statistically significant differences between the groups regarding neurological, renal or cardiac complications. Patients in hypothermia required less catecholamine at the end of the operation (p = 0.00001), but there was no significant difference in the length of the stay in the intensive care unit between the groups. Cardiopulmonary bypass temperature did not influence early outcome after aortic valve surgery.
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Tosson et al. (2001) conducted a cohort in Aortic valve surgery (n=323). Normothermia vs. Moderate hypothermia (28 degrees C) was evaluated on Neurological, renal or cardiac complications. Normothermia during aortic valve surgery did not influence early neurological, renal, or cardiac complications compared to hypothermia, though hypothermia required less catecholamine (p=0.00001).
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