Key result
Childhood obesity and overweight increased the odds of testing positive for SARS-CoV-2 compared to a healthy body mass index (OR 1.07-1.12 and 1.06-1.08, respectively).
Why the study?
The study was conducted to determine the effects of childhood obesity on SARS-CoV-2 infection.
Does obesity or overweight increase the risk of SARS-CoV-2 infection in children?
Cross-Sectional (n=444,868)
Does obesity or overweight increase the risk of SARS-CoV-2 infection in children?
Effect estimate: OR 1.07-1.12
Excess weight in childhood is associated with a slightly increased risk of testing positive for SARS-CoV-2.
Slightly higher positivity odds warrant no practice change; leaves open prospective confirmation of infection risk.
AIM: To determine the effects of obesity in childhood on SARS-CoV-2 infection. METHODS: A population-based, cross-sectional study combining the Israeli Growth Survey and COVID-19 data for children with at least one SARS-CoV-2 test from 16 February 2020 to 20 December 2021. Overweight and obesity status were based on body mass index and the Center for Disease Control criteria. Multivariate logistics regression was performed to validate reliability for weight categories at the age of approximately 6 years compared with weights at approximately 12 years. RESULTS: A total of 444 868 records for children with an overall positivity rate of 22% were studied. The mean age was 9.5 years. The odds ratios of children with obesity or overweight after controlling for sex at 6 years to test positive were 1.07-1.12 and 1.06-1.08 (depending on the model), respectively, compared to those with healthy range body mass index. CONCLUSION: Excess weight appears to increase the risk of SARS-CoV-2 infection. This finding should be considered for public health planning. For example, children with overweight and obesity should be prioritised for vaccination. Excess weight in childhood can be harmful at a young age and not only for long-term health.
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Zimmerman et al. (2023) conducted a cross-sectional in SARS-CoV-2 infection (n=444,868). Obesity or overweight vs. Healthy range body mass index was evaluated on SARS-CoV-2 test positivity (OR 1.07-1.12). Childhood obesity and overweight increased the odds of testing positive for SARS-CoV-2 compared to a healthy body mass index (OR 1.07-1.12 and 1.06-1.08, respectively).
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