Key result
A 41-year-old woman developed fatal catastrophic intracardiac thrombosis following prolonged cardiopulmonary bypass and administration of procoagulant agents during emergency repair of an expanding aortic pseudoaneurysm.
Why the study?
Catastrophic thrombosis is a rare and frequently fatal event following complex cardiac surgery, often occurring after CPB separation and reversal of anticoagulation.
Case Report (n=1)
No
Highlights the rare but severe risk of catastrophic intracardiac thrombosis associated with hemostatic blood products and procoagulant agents after cardiopulmonary bypass.
Answers are grounded in this paper and cite their sources.
Raises awareness of paradoxical post-CPB thrombosis during bleeding treatment; leaves open optimal management strategies in complex aortic surgery.
Catastrophic thrombosis is a rare but frequently fatal event following complex cardiac surgery. It is most often encountered following separation from cardiopulmonary bypass (CPB) and reversal of heparin anticoagulation, and somewhat paradoxically, at the time when bleeding from post-CPB coagulopathy is being treated. We report the case of a 41-year-old female taken to the operating room for repair of an expanding ascending aortic pseudoaneurysm. Following a prolonged operation, she developed intracardiac thrombus during transfusion of hemostatic blood products and procoagulant agents. Potential contributing factors are discussed.
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Vadlamudi et al. (2019) conducted a case report in Expanding aortic pseudoaneurysm (n=1). Emergency repair with cardiopulmonary bypass and procoagulant therapy was evaluated on Intracardiac thrombosis. A 41-year-old woman developed fatal catastrophic intracardiac thrombosis following prolonged cardiopulmonary bypass and administration of procoagulant agents during emergency repair of an expanding aortic pseudoaneurysm.
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