Key result
Molecular imaging techniques, particularly hybrid PET/CT, provide valuable complementary functional information to conventional anatomical imaging for the biopsy guidance, staging, and therapeutic monitoring of sarcomas.
Why the study?
Do molecular imaging techniques like PET/CT provide complementary information to conventional imaging in the evaluation and management of sarcomas?
Do molecular imaging techniques like PET/CT provide complementary information to conventional imaging in the evaluation and management of sarcomas?
Molecular imaging techniques such as PET/CT provide valuable complementary information to conventional imaging for the staging, biopsy guidance, and treatment response assessment of sarcomas.
May aid sarcoma staging and monitoring; leaves open need for prospective validation before practice change.
A wide range of molecular imaging techniques are available that can provide complementary information to conventional, anatomical imaging for the evaluation of known or suspected bone and soft tissue sarcomas. In particular, positron emission tomography (PET), particularly in the form of hybrid PET/CT technology, offers many potential advantages over current imaging approaches by delineating not only the extent of disease but also the biological heterogeneity that can exist both between and within sarcomas. This review discusses the clinical situations where nuclear medicine techniques can aid in the management of patients with sarcoma. These include biopsy guidance, whole body staging, therapeutic response assessment and evaluation of residual mass lesions after treatment.
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Rodney J. Hicks (2005) conducted a review in Bone and soft tissue sarcomas. Molecular imaging (PET, PET/CT, single-photon techniques) vs. Conventional anatomical imaging was evaluated. Molecular imaging techniques, particularly hybrid PET/CT, provide valuable complementary functional information to conventional anatomical imaging for the biopsy guidance, staging, and therapeutic monitoring of sarcomas.
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