Cerebroplacental Doppler Ratio in Prediction of Adverse Perinatal Outcome in Full Term Normal Pregnancy

Background: The cerebroplacental ratio (CPR) may be able to detect fetus that do not develops fully at term and predict poor pregnancy outcomes. In third-trimester studies of high-risk pregnancies, low CRP due to increased umbilical artery (UA) or fetus middle cerebral artery pulsatility index (MCA-PI) has been linked to poor pregnancy outcomes. . Objective: To assess the predictive utility of doppler CPR for screening of full-term (37 week - 40 week) normal un-complicated pregnancies with a bad outcome. Methodology: This observational hospital based cross sectional study was conducted on 500 women normal uncomplicated full-term pregnancy (37- 40 weeks), giving birth at Al-Zahraa university hospital and Elsinbelaween general hospital from June 2021 to June 2022. All women were subjected to measurement of abdominal ultrasound, femur length (FL), abdominal circumference (AC), gestational age, complete, cardiotocography (CTG) to assess fetal, and umbilical and placental doppler for middle cerebral artery (MCA) and umbilical artery (UA). Results: MCA systolic / diastolic (S/D) ratio was inversely correlated with pCO2, while UA-S/D ratio was positively correlated with pCO2 and negatively correlated with all other parameters except neonatal death and neonatal intensive care unit admission. Conclusion: In full-term normal pregnancy, the CPR is an excellent predictor of unfavorable perinatal outcome