Key result
Isovolemic cross-circulation between DOCA and NaD rats restored the depressed renal response of NaD rats to blood volume expansion, suggesting the transfer of a humoral factor.
Cross-circulation experiments in rats suggest the existence of a humoral factor that modifies the renal response to blood volume expansion.
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Hypothesis-generating for a humoral factor in volume regulation; leaves open its identity and human relevance.
Pearce et al. (1969) studied Renal response to blood volume expansion. Isovolemic cross-circulation vs. Exchange without cross-circulation was evaluated on Renal response to blood volume expansion. Isovolemic cross-circulation between DOCA and NaD rats restored the depressed renal response of NaD rats to blood volume expansion, suggesting the transfer of a humoral factor.
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