Key result
Comprehensive functional assessment of the fetal heart using cardiovascular and biophysical profile scores with Doppler echocardiography improves characterization of congenital heart disease in utero.
Why the study?
Does comprehensive functional assessment improve the characterization and monitoring of congenital heart disease in utero?
Does comprehensive functional assessment improve the characterization and monitoring of congenital heart disease in utero?
Comprehensive fetal echocardiographic and physiological assessment is necessary to monitor the evolution of congenital heart disease in utero, guide interventions, and predict perinatal outcomes.
May support refined in utero monitoring of congenital heart disease; leaves open need for prospective validation before guiding interventions.
PURPOSE OF REVIEW: This article reviews recent developments in the assessment of changes in structure and function in the fetal heart with the focus on congenital heart disease malformations. RECENT FINDINGS: Use of the combination of the cardiovascular profile score, the biophysical profile score and additional physiological measurements with Doppler echocardiography have allowed better characterization of disease states and the changes that can occur in utero during the last two trimesters of gestation. SUMMARY: A comprehensive examination of the structure and function of the fetal heart together with the evaluation of other parameters of fetal wellbeing are necessary for comprehensive assessment of the evolution of congenital heart disease in utero. Only such an objective surveillance can elucidate the pathophysiology and natural history, guide appropriate timing of intervention, monitor the success of any in-utero therapy, and predict perinatal outcome.
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Acharya et al. (2007) conducted a review in Congenital heart disease malformations in utero. Functional assessment using cardiovascular profile score, biophysical profile score, and Doppler echocardiography was evaluated. Comprehensive functional assessment of the fetal heart using cardiovascular and biophysical profile scores with Doppler echocardiography improves characterization of congenital heart disease in utero.
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