Key result
Uterine artery pulsatility index at 20-24 weeks' gestation was inversely associated with gestational age at delivery and birth weight Z-score in pregnancies with preeclampsia (p < 0.0001).
Why the study?
Does uterine artery pulsatility index at 20-24 weeks' gestation predict the severity of preeclampsia in singleton pregnancies?
Population
50,490 singleton pregnancies at 20-24 weeks' gestation, including 1,442 that developed preeclampsia.
Design
Cohort
Follow-up
Until delivery
Authors
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May aid severity stratification in preeclampsia; leaves open prospective validation before changing surveillance.
Cohort (n=50,490)
Does uterine artery pulsatility index at 20-24 weeks' gestation predict the severity of preeclampsia in singleton pregnancies?
p-value: p=<0.0001
Uterine artery pulsatility index measured at 20-24 weeks' gestation is significantly associated with the severity of preeclampsia, including earlier gestational age at delivery and lower birth weight.
Gallo et al. (2013) conducted a cohort in Preeclampsia (n=50,490). Uterine artery pulsatility index (PI) vs. Normal pregnancies was evaluated on Association between uterine artery PI MoM and gestational age at delivery and birth weight Z-score in preeclampsia (p=<0.0001). Uterine artery pulsatility index at 20-24 weeks' gestation was inversely associated with gestational age at delivery and birth weight Z-score in pregnancies with preeclampsia (p < 0.0001).
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