Key result
Natural IFN-alpha therapy yielded a complete response in 38% of children with chronic hepatitis C and a history of acute leukemia.
Why the study?
Does interferon-alpha improve complete response rates in children with chronic hepatitis C and a history of acute leukemia?
Does interferon-alpha improve complete response rates in children with chronic hepatitis C and a history of acute leukemia?
Interferon-alpha therapy achieved a 38% complete response rate in children with chronic hepatitis C and a history of acute leukemia, though one patient developed transient heart failure.
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May support IFN-alpha consideration in this rare subgroup; case-report data leave efficacy and cardiac safety unresolved.
Komatsu et al. (1996) studied Chronic hepatitis C with a history of acute leukemia (n=13). Natural IFN-alpha was evaluated on Complete response. Natural IFN-alpha therapy yielded a complete response in 38% of children with chronic hepatitis C and a history of acute leukemia.
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