Key result
Opioid-free anesthesia is a feasible approach for laparoscopic treatment, though evidence-based data on its clinical benefits and potential complications remain limited.
Why the study?
There are limited literature data regarding the clinical benefits, side effects, and potential complications associated with opioid-free anesthesia.
Does opioid-free anesthesia provide clinical benefits and reduce side effects in patients undergoing laparoscopic treatment?
Does opioid-free anesthesia provide clinical benefits and reduce side effects in patients undergoing laparoscopic treatment?
This review summarizes the physiological rationale and current evidence regarding the benefits and risks of opioid-free anesthesia in laparoscopic surgery.
Opioid-free anesthesia in laparoscopic surgery remains hypothesis-generating; randomized trials are needed before clinical adoption.
Opioid-free anesthesia (OFA) is currently a new scientific perspective. This approach is based on the concept of multimodal anesthesia and desire to avoid the negative impact of intraoperative opioid administration. Some studies suggest that OFA is feasible. However, there are still few literature data on clinical benefits and side effects and/or complications potentially associated with OFA. This review is devoted to physiology of nociception, causes for using or avoiding opioids for anesthesia and evidence-based data on benefits and risks of this approach.
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Buchatskaya et al. (2023) conducted a review in Anesthesia for laparoscopic treatment. Opioid-free anesthesia was evaluated. Opioid-free anesthesia is a feasible approach for laparoscopic treatment, though evidence-based data on its clinical benefits and potential complications remain limited.
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