Key result
Evidence that carbon dioxide insufflation during cardiac surgery reduces postoperative neurocognitive decline is scant, prompting this systematic review.
Why the study?
Does carbon dioxide insufflation reduce postoperative neurocognitive decline in patients undergoing cardiac surgery?
Systematic Review
Does carbon dioxide insufflation reduce postoperative neurocognitive decline in patients undergoing cardiac surgery?
This systematic review aims to evaluate the scant evidence regarding whether carbon dioxide insufflation during cardiac surgery reduces postoperative neurocognitive decline.
Scant evidence precludes routine carbon dioxide insufflation for neuroprotection in cardiac surgery; leaves open the need for definitive RCTs.
The use of carbon dioxide (CO(2)) insufflation into the pericardial well has become widespread, and in some units routine. The rationale behind this practice is the fact that CO(2) is more soluble than air leading to fewer gaseous microemboli entering the bloodstream and being transferred to the brain or heart. However, the evidence that this reduces postoperative neurocognitive decline is scant. Although CO(2) insufflation is generally a safe procedure there are case reports of significant complications. The aim of this systematic review is to analyze the current evidence for this practice.
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Chaudhuri et al. (2011) conducted a systematic review in Cardiac Surgery. Carbon dioxide (CO2) insufflation was evaluated on postoperative neurocognitive decline. Evidence that carbon dioxide insufflation during cardiac surgery reduces postoperative neurocognitive decline is scant, prompting this systematic review.
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