Key result
Autoradiographs of frog toe muscles soaked in Ca(45) showed that grain density over the A bands was mostly over myofibrils, while over the I bands it was greatest between myofibrils.
Population
Frog toe muscles
Design
Preclinical
Authors
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These amphibian localization patterns are hypothesis-generating; leaves open relevance to mammalian muscle physiology.
Autoradiography reveals specific localization patterns of calcium within the A and I bands of frog skeletal muscle myofibrils.
Saul Winegrad (1965) studied this question. Ca(45) soaking and osmium-oxalate fixation was evaluated on Location of muscle calcium (grain density distribution). Autoradiographs of frog toe muscles soaked in Ca(45) showed that grain density over the A bands was mostly over myofibrils, while over the I bands it was greatest between myofibrils.
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