EDITORIAL SYNOPSIS Raised urinary oestrogen excretion was noted in 16 men and women with liver disease.The study suggests that the increased output of urinary oestrogens was usually due to increased secretion rates of the primary oestrogenic hormones rather than to impaired oestrogen metabolism by the liver.11, and 12. Endocrine changes were also observed as follows: gynaecomastia (cases 1 and 4), testicular atrophy 56 on August 20,
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Brown et al. (1964) studied this question.
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