Key result
Prolonged bypass time (≥100 minutes) during coronary artery bypass graft surgery was associated with substantially higher operative mortality compared to average bypass time (10.3% vs 0.63%).
Why the study?
What factors influence operative mortality and postoperative myocardial infarction in patients undergoing first-time coronary artery bypass graft surgery?
Population
12,003 patients undergoing first-time coronary artery bypass graft (CABG) surgery only, between 1978 and 1990.
Design
Cohort
Follow-up
Operative and postoperative period
Authors
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Prolonged bypass time flags higher CABG mortality risk; leaves open whether shortening perfusion time improves outcomes.
Cohort (n=12,003)
No
What factors influence operative mortality and postoperative myocardial infarction in patients undergoing first-time coronary artery bypass graft surgery?
Absolute Event Rate: 10.3% vs 0.63%
Prolonged perfusion time and the presence of unstable angina are major risk factors for operative mortality and postoperative myocardial infarction in patients undergoing first-time CABG.
Iyer et al. (1993) conducted a cohort in Coronary artery disease requiring bypass surgery (n=12,003). Prolonged bypass time (≥100 minutes) vs. Average bypass time (48 minutes) was evaluated on Operative mortality. Prolonged bypass time (≥100 minutes) during coronary artery bypass graft surgery was associated with substantially higher operative mortality compared to average bypass time (10.3% vs 0.63%).
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