Studies on the Components of Atractylodes. II. New Polyacetylenic compounds in the Rhizome of Atractylodes lancea DE CANDOLLE var.chinensis KITAMURA

Two new polyacetylenic compounds, named atractylodinol and acetylatractylodinol, were isolated from the rhizome of Atractylodes lancea DE CANDOLLE var.chinensis KITAMURA (Compositae), together with atractylodin. Their structures were determined from spectroscopic and chemical evidences. They were found to show piscicidal activity against Oryzias latipes TEMMINK et SCHLEGEL, the median tolerance limit (24 hr) of atractylodinol was 1.8 ppm and that of atractylodin, 3.0 ppm.