Key result
PT, PT + APTT, and PT/APTT ratios predicted ISTH DIC scores in inpatients with suspected DIC, whereas APTT alone did not.
Why the study?
Do PT, APTT, and their combinations predict the ISTH DIC score in inpatients with suspected DIC?
Observational (n=50)
Do PT, APTT, and their combinations predict the ISTH DIC score in inpatients with suspected DIC?
Answers are grounded in this paper and cite their sources.
PT and its combinations with APTT can significantly predict ISTH DIC scores without the need for d-dimer levels or platelet counts.
We looked into the statistical association of prothrombin time (PT) and activated partial thromboplastin time (APTT) with disseminated intravascular coagulation (DIC) score calculated using the International society for thrombosis and haemostasis (ISTH) scoring system. The PT, APTT, PT + APTT, and PT/APTT ratios were evaluated against the DIC score by linear regression analysis in fifty inpatients with suspected DIC. The PT, PT + APTT, and PT/APTT ratios were all found to be statistically significant in predicting DIC scores with P values of 0.02, 0.03, and 0.02, respectively. The APTT alone was not found to be statistically significant in predicting DIC score and had a P value of 0.09. This scoring system does not need d-dimer levels and the platelet count.
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Vani Chandrashekar (2012) conducted an observational in Suspected disseminated intravascular coagulation (DIC) (n=50). PT, APTT, PT + APTT, and PT/APTT ratios was evaluated on DIC score calculated using the ISTH scoring system (p=0.02, 0.03, and 0.02). PT, PT + APTT, and PT/APTT ratios predicted ISTH DIC scores in inpatients with suspected DIC, whereas APTT alone did not.
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