Key result
Therapy with penicillin, heparin, epsilon-aminocaproic acid, and hydrocortisone resulted in rapid reversal of coagulation factor abnormalities and a favorable outcome in a child with meningococcemia.
Population
1 child with fulminant meningococcemia and diffuse intravascular clotting
Design
Case_report
Authors
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Hypothesis-generating for heparin-inclusive regimens in pediatric meningococcemia with DIC; prospective trials required before practice change.
Case Report (n=1)
In a child with fulminant meningococcemia and diffuse intravascular clotting, combination therapy including heparin rapidly reversed coagulation abnormalities.
Abildgaard et al. (1967) conducted a case report in Fulminant meningococcemia with diffuse intravascular clotting (n=1). Penicillin, heparin, epsilon-aminocaproic acid, and hydrocortisone was evaluated on Reversal of coagulation factor abnormalities and clinical outcome. Therapy with penicillin, heparin, epsilon-aminocaproic acid, and hydrocortisone resulted in rapid reversal of coagulation factor abnormalities and a favorable outcome in a child with meningococcemia.
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