Key result
Complex congenital heart disease or pulmonary artery hypertension was associated with significantly increased odds of poor quality of life (OR 4.55) compared to simple congenital heart disease.
Why the study?
Little is known about the quality of life and health status of adults with congenital heart disease in developing countries.
Cross-Sectional (n=109)
No
Odds Ratio: 4.55 (95% CI 1.26–16.4)
Absolute Event Rate: 31.3% vs 8.6%
p-value: p=0.021
Adults with congenital heart disease in Vietnam experience low quality of life and high levels of anxiety and depression, which are associated with complex disease, unemployment, and being unmarried.
QOL data for adults with CHD in Vietnam remain sparse; hypothesis-generating and should not yet change practice.
Background: Little is known about the quality of life (QOL) and health status of adults with congenital heart disease (CHD) in developing countries. Therefore, this study aimed to describe the QOL and health status of adults with CHD and investigate the association between QOL and biological and social characteristics of these patients in Vietnam.Methods: A cross-sectional study was performed among 109 adults with CHD, hospitalised in the Vietnam National Heart Institute, between June 2019 and December 2019. Validated instruments to assess QOL and health status describing patient-reported outcomes were used, including the EuroQOL-5 Dimensions-5 Level, Satisfaction with Life Scale and Hospital Anxiety and Depression Scale.Results: The overall mean scores on the EuroQOL-descriptive system (EQ-DS) and the EuroQOL visual analogue scale (EQ-VAS) were 0.792 (SD = 0.122, 95% confidence interval, CI 0.769–0.815) and 66.3 (SD = 12.5, 95% CI 63.9–68.7), respectively. Symptoms of anxiety and depression were common among adults with CHD (18.7%, n = 20 and 11%, n = 12; respectively). Stratified multivariate logistic regression revealed: poor QOL using the EQ-DS, and that anxiety related to suffering from a complex CHD/ pulmonary artery hypertension (PAH) (Odds Ratio, OR = 4.55, 95% CI: 1.26–16.4, p = 0.021 and OR = 4.19, 95% CI 1.2–14.56, p = 0.024; respectively); poor QOL using the EQ-VAS, anxiety, and depression related to being unemployed/ unstable employment (OR = 4.16, 95% CI 1.64–10.56, p = 0.003; OR = 3.63, 95% CI 1.23–10.72, p = 0.02 and OR = 7.68, 95% CI 2.09–28.25, p = 0.002; respectively); and life dissatisfaction related to being unmarried (OR = 4.63, 95% CI 1.2–17.86, p = 0.026).Conclusions: Adults with CHD in Vietnam experienced low QOL, and high levels of anxiety and depression. Poor QOL and psychological problems were related to being female, unmarried, low educational level, unemployed/ unstable employ, and complex CHD/ PAH.
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Truong et al. (2021) conducted a cross-sectional in Congenital Heart Disease (n=109). Complex congenital heart disease or pulmonary artery hypertension vs. Simple congenital heart disease was evaluated on Poor quality of life (EQ-DS < 0.65) (OR 4.55, 95% CI 1.26-16.4, p=0.021). Complex congenital heart disease or pulmonary artery hypertension was associated with significantly increased odds of poor quality of life (OR 4.55) compared to simple congenital heart disease.
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