Key result
Preoperative left stellate ganglion block significantly reduced the incidence of intraoperative arrhythmias during off-pump CABG compared to control (20% in the block group; P=0.007).
Why the study?
Cardiac arrhythmias are common during and after CABG surgery, but the preventive effect of stellate ganglion block specifically on intraoperative arrhythmias during off-pump CABG surgery had not been evaluated as a primary focus.
Does preoperative left stellate ganglion block reduce intraoperative arrhythmias in adult patients undergoing elective off-pump CABG surgery?
RCT (n=40)
randomized
Does preoperative left stellate ganglion block reduce intraoperative arrhythmias in adult patients undergoing elective off-pump CABG surgery?
p-value: p=0.007
Preoperative left stellate ganglion block with lidocaine significantly reduces the incidence of intraoperative arrhythmias during off-pump CABG surgery.
Preoperative left SGB may lower intraoperative arrhythmia risk in off-pump CABG; extends preliminary data but requires larger confirmatory trials.
Background Cardiac arrhythmias are not uncommon during and after coronary artery bypass graft cardiac surgeries. Preliminary studies showed the preventive effects of stellate ganglion block upon cardiac arrhythmias; however, this could be the 1st study focusing upon intraoperative arrhythmias during offpump coronary artery bypass graft surgery as a main goal.Methods This is a randomized controlled trial. The study involved forty adult patients undergoing elective offpump coronary artery bypass graft surgery. Twenty patients received left SGB with 10 ml of 2% lidocaine before induction of anesthesia (B group), and twenty patients as a control group (A group). Intraoperative and 24-hours postoperative electrocardiogram and hemodynamics were monitored, in addition to the mean postoperative 24-hours inotropic score.Results There was a significantly higher incidence of intraoperative arrhythmias in the control group in the form of bradyarrhythmia (25%), supraventricular tachycardia (30%), atrial fibrillation (5%), ventricular tachycardia (10%), and ventricular fibrillation (5%) in comparison to the block group where atrial fibrillation occurred only in 4 patients (20%) with the p value of 0.007. Mean arterial blood pressure and heart rate showed significantly lower values in the SGB group intraoperatively. Postoperative mean 24-hour inotropic score and hemodynamics showed insignificant differences.Conclusion Preoperative left stellate ganglion block can decrease incidence of arrhythmias during offpump coronary artery bypass graft surgeries. The technique showed a safe profile upon hemodynamics during the study period.
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Allah et al. (2020) conducted an RCT in elective off-pump coronary artery bypass graft surgery (n=40). left stellate ganglion block vs. control was evaluated on intraoperative arrhythmias (p=0.007). Preoperative left stellate ganglion block significantly reduced the incidence of intraoperative arrhythmias during off-pump CABG compared to control (20% in the block group; P=0.007).
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