What does this research mean for the field?

A standardized protocol utilizing specific visual criteria enables accurate and consistent manual realignment of structural MR images to the clinically used Schaltenbrand AC-PC plane. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To establish and validate a standardized protocol (ACPC-MAP) for manually realigning structural T1-weighted MR images to the clinically utilized Schaltenbrand anterior commissure–posterior commissure plane.

August 30, 2026Brain Structure and FunctionOpen Access

ACPC-MAP: a protocol for manually aligning structural T1-weighted magnetic resonance images to the anterior commissure – posterior commissure plane according to clinical standards

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Authors

ASAshok K. Selvaraj RBRonald Bartels CBChristian Beckmann

Discussion

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Overview

Methodological study demonstrates a standardized protocol for manually aligning structural MRI to the clinical AC-PC plane, highlighting improved consistency across research and neurosurgery.

Key Points

To establish and validate a standardized protocol (ACPC-MAP) for manually realigning structural T1-weighted MR images to the clinically utilized Schaltenbrand anterior commissure–posterior commissure plane.
Formulated standardized visual anatomical criteria to guide the manual orientation and alignment of structural T1-weighted MR images to the Schaltenbrand AC-PC stereotactic axis.
Structured the protocol to resolve inconsistencies between neurosurgical standards and neuroimaging research atlases like Talairach, providing an explicit workflow for human raters.
Yielded an explicit, reproducible manual alignment system to overcome discrepancies between varied AC-PC definitions used across clinical and neuroimaging domains.
Provided a standardized method to verify automated alignment outcomes, correct failures in automated processing pipelines, and generate high-fidelity ground truth reference data.

Cite This Study

Selvaraj et al. (2026) studied this question.

synapsesocial.com/papers/6a93efc06c1a8fb52e79bc47 https://doi.org/10.1007/s00429-026-03171-z

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August 30, 2026Brain Structure and FunctionOpen Access

ACPC-MAP: a protocol for manually aligning structural T1-weighted magnetic resonance images to the anterior commissure – posterior commissure plane according to clinical standards

View Full Paper

Ask AI

Bookmark

Authors

ASAshok K. Selvaraj RBRonald Bartels CBChristian Beckmann

Discussion

Member takes

Overview

Methodological study demonstrates a standardized protocol for manually aligning structural MRI to the clinical AC-PC plane, highlighting improved consistency across research and neurosurgery.

Key Points

To establish and validate a standardized protocol (ACPC-MAP) for manually realigning structural T1-weighted MR images to the clinically utilized Schaltenbrand anterior commissure–posterior commissure plane.
Formulated standardized visual anatomical criteria to guide the manual orientation and alignment of structural T1-weighted MR images to the Schaltenbrand AC-PC stereotactic axis.
Structured the protocol to resolve inconsistencies between neurosurgical standards and neuroimaging research atlases like Talairach, providing an explicit workflow for human raters.
Yielded an explicit, reproducible manual alignment system to overcome discrepancies between varied AC-PC definitions used across clinical and neuroimaging domains.
Provided a standardized method to verify automated alignment outcomes, correct failures in automated processing pipelines, and generate high-fidelity ground truth reference data.

Cite This Study

Selvaraj et al. (2026) studied this question.

synapsesocial.com/papers/6a93efc06c1a8fb52e79bc47 https://doi.org/10.1007/s00429-026-03171-z

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

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