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August 30, 2026Journal of Oral Biology and Craniofacial ResearchOpen Access

Isolated oral pemphigus vegetans - A case report

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Authors

SHSonam HaldankarGoa Dental College and HospitalNRNairica RebelloGoa Dental College and HospitalASAnita SpadigamGoa Dental College and Hospital

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Implication

Case report demonstrates successful corticosteroid management of isolated oral pemphigus vegetans in a middle-aged female, highlighting the importance of identifying atypical disease presentations.

Key Points

  • To describe the clinical presentation, diagnostic evaluation, and therapeutic outcome of an atypical case of isolated oral pemphigus vegetans on the tongue.
  • Evaluated a 55-year-old female presenting with a three-month history of recurring tongue blisters that developed into persistent vegetative plaques.
  • Performed clinical, hematological, and histopathological assessments to confirm the diagnosis.
  • Treated the patient with a therapeutic regimen consisting of systemic corticosteroids, topical corticosteroids, and adjunctive therapies.
  • Histopathological, hematological, and clinical evaluations confirmed the diagnosis of pemphigus vegetans presenting strictly in the oral cavity.
  • The patient achieved marked clinical improvement within weeks of starting systemic and topical corticosteroid therapy.

Cite This Study

Haldankar et al. (2026) studied this question.

synapsesocial.com/papers/6a93f0a36c1a8fb52e79cf41https://doi.org/10.1016/j.jobcr.2026.101527
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Two Cases of Pemphigus Vegetans With IgG Anti–Desmocollin 3 Antibodies2013 · 32 citations
  2. 2Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site2024 · 15 citations
  3. 3Oral pemphigus vegetans: A case report2012 · 3 citations
  4. 4Assessing the use of methotrexate as an alternate therapy for pemphigus vulgaris and pemphigus foliaceus2022 · 4 citations