What does this research mean for the field?

Prehabilitative exercise before oncologic surgery significantly improves preoperative cardiorespiratory fitness, physical function, and quality of life, while reducing fatigue and attenuating perioperative functional decline. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 30, 2026Journal of Cancer SurvivorshipOpen Access

Benefits of prehabilitative exercise on physiological, functional and patient-reported outcomes in patients undergoing oncologic surgery: A systematic review and meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

NCNatália Casagrande FSFavil Singh ARAnderson Rech

Discussion

Member takes

Overview

Systematic review and meta-analysis reveals prehabilitation improves fitness and function in oncologic surgery patients, suggesting structured exercise mitigates perioperative deconditioning.

Key Points

To assess the effects of prehabilitative exercise on physiological, functional, and patient-reported outcomes in patients undergoing oncologic surgery.
Conducted a systematic review and three-level mixed-effects meta-analysis (PROSPERO: CRD420251072796) searching seven databases through June 2025.
Included 27 randomized controlled trials involving 2,005 adults that compared structured prehabilitative exercise interventions against usual care prior to cancer surgery.
Prehabilitation significantly improved cardiorespiratory fitness (SMD 0.31, p = 0.010), physical function (SMD 0.36, p < 0.001), and quality of life (SMD 0.19, p = 0.030), with sustained physical function benefits postoperatively.
Preoperative fatigue was significantly reduced (SMD –0.21, p = 0.017), whereas muscle strength and psychological distress were preserved relative to baseline.
The overall certainty of evidence across evaluated outcomes ranged from very low to moderate.

Cite This Study

Casagrande et al. (2026) studied this question.

synapsesocial.com/papers/6a93f14b6c1a8fb52e79e2ec https://doi.org/10.1007/s11764-026-02107-0

View Full Paper

Ask AI

Bookmark

August 30, 2026Journal of Cancer SurvivorshipOpen Access

Benefits of prehabilitative exercise on physiological, functional and patient-reported outcomes in patients undergoing oncologic surgery: A systematic review and meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

NCNatália Casagrande FSFavil Singh ARAnderson Rech

Discussion

Member takes

Overview

Systematic review and meta-analysis reveals prehabilitation improves fitness and function in oncologic surgery patients, suggesting structured exercise mitigates perioperative deconditioning.

Key Points

To assess the effects of prehabilitative exercise on physiological, functional, and patient-reported outcomes in patients undergoing oncologic surgery.
Conducted a systematic review and three-level mixed-effects meta-analysis (PROSPERO: CRD420251072796) searching seven databases through June 2025.
Included 27 randomized controlled trials involving 2,005 adults that compared structured prehabilitative exercise interventions against usual care prior to cancer surgery.
Prehabilitation significantly improved cardiorespiratory fitness (SMD 0.31, p = 0.010), physical function (SMD 0.36, p < 0.001), and quality of life (SMD 0.19, p = 0.030), with sustained physical function benefits postoperatively.
Preoperative fatigue was significantly reduced (SMD –0.21, p = 0.017), whereas muscle strength and psychological distress were preserved relative to baseline.
The overall certainty of evidence across evaluated outcomes ranged from very low to moderate.

Cite This Study

Casagrande et al. (2026) studied this question.

synapsesocial.com/papers/6a93f14b6c1a8fb52e79e2ec https://doi.org/10.1007/s11764-026-02107-0

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark