Anderson Type Na3[AlMo6O24H6]·8H2O: Novel and Green Catalyst for Quinoxaline Synthesis and Biomedical Applications

Anderson-type sodium hexamolybdoaluminate(III) is used for the synthesis of quinoxaline derivatives using 1,2-diketone and 1,2-diamine in aqueous medium at room temperature. This catalyst is characterized by using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and thermogravimetric analysis (TGA). The Al(III) catalyst is a heterogeneous catalyst that was successfully recovered and recycled four times without major loss of activity. The methodology is environmentally benign and offers excellent product yields. The (Na3[AlMo6O24H6]·8H2O) is biologically evaluated for its cytotoxic activity against human breast adenocarcinoma cell lines. This catalyst exhibited moderate cytotoxic activity compared to the standard drug 5‑fluorouracil (5-FU), with a cell viability of 62.48% and an IC50 value of 144.573 μg/mL.