Key result
Postoperative venous thromboembolism after CABG was associated with higher inpatient mortality compared to no VTE (6.8% vs 1.7%; adjusted OR 1.92; 95% CI 1.40-2.65; P<0.001).
Why the study?
Venous thromboembolism prophylaxis after CABG is controversial due to perceived low incidence and bleeding risk, and prior studies may have been underpowered to assess VTE outcomes.
Does acute venous thromboembolism worsen in-hospital outcomes in patients undergoing CABG?
Population
331 950 patients >18 years of age undergoing CABG without concomitant valvular procedures
Comparison
Postoperative VTE vs no VTE during hospital stay
Design
National inpatient database retrospective study
Authors
Loading...
VTE vigilance may be prudent post-CABG; leaves open whether prevention reduces mortality in trials.
Observational (n=331,950)
Yes
Does acute venous thromboembolism worsen in-hospital outcomes in patients undergoing CABG?
Odds Ratio: 1.92 (95% CI 1.4–2.65)
Absolute Event Rate: 6.8% vs 1.7%
p-value: p=<0.001
Although postoperative VTE after CABG is rare (1.3%), it is associated with significantly increased inpatient mortality, complications, cost, and length of stay.
Panhwar et al. (2019) conducted an observational in Coronary Artery Bypass Graft Surgery (n=331,950). Venous thromboembolism (VTE) vs. No VTE was evaluated on inpatient mortality (OR 1.92, 95% CI 1.40-2.65, p=<0.001). Postoperative venous thromboembolism after CABG was associated with higher inpatient mortality compared to no VTE (6.8% vs 1.7%; adjusted OR 1.92; 95% CI 1.40-2.65; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: