Key result
On-pump valve replacement was associated with a generalized increase in beta power and delta-1 mean frequency on EEG at two weeks postoperatively compared to healthy spouse controls.
Why the study?
Does on-pump valve replacement surgery cause brain ischemic alterations as assessed by EEG compared to controls?
Case-Control (n=22)
Does on-pump valve replacement surgery cause brain ischemic alterations as assessed by EEG compared to controls?
On-pump valve replacement is associated with postoperative EEG changes that may indicate cortical dysfunction and intraoperative ischemia.
May signal cortical dysfunction after on-pump valve replacement; leaves open whether EEG changes reflect ischemia or warrant monitoring.
Cardiac surgery is commonly associated with brain ischemia. Few studies addressed brain electric activity changes after on-pump operations. Eyes closed EEG was performed in 22 patients (mean age: 45.2 ± 11.2) before and two weeks after valve replacement. Spouses of patients were invited to participate as controls. Generalized increase of beta power most prominent in beta-1 band was an unambiguous pathological sign of postoperative cortex dysfunction, probably, manifesting due to gamma-activity slowing ("beta buzz" symptom). Generalized postoperative increase of delta-1 mean frequency along with increase of slow-wave activity in right posterior region may be hypothesized to be a consequence of intraoperative ischemia as well. At the same time, significant changes of alpha activity were observed in both patient and control groups, and, therefore, may be considered as physiological. Unexpectedly, controls showed prominent increase of electric activity in left temporal region whereas patients were deficient in left hemisphere activity in comparison with controls at postoperative followup. Further research is needed in order to determine the true neurological meaning of the EEG findings after on-pump operations.
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Голухова et al. (2011) conducted a case-control in Valve replacement (n=22). On-pump valve replacement vs. Spouses of patients was evaluated on Brain electric activity changes on EEG. On-pump valve replacement was associated with a generalized increase in beta power and delta-1 mean frequency on EEG at two weeks postoperatively compared to healthy spouse controls.
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