Key result
Control of hypertension with antihypertensive drugs was inadequate, achieved in only 2.83% of patients with complicated kidney disease and 14.33% with non-complicated kidney disease.
Why the study?
Does antihypertensive drug treatment adequately control blood pressure in adult patients undergoing maintenance hemodialysis?
Cohort (n=100)
Does antihypertensive drug treatment adequately control blood pressure in adult patients undergoing maintenance hemodialysis?
Blood pressure control remains highly inadequate in patients undergoing maintenance hemodialysis despite the use of antihypertensive medications.
Inadequate BP control persists in hemodialysis patients on antihypertensives; this Level 3 cohort finding leaves open optimized regimens for prospective trials.
Introduction: Hypertension is the second leading cause of End Stage Renal Disease after diabetes mellitus. If hypertension is an etiologically significant cardiovascular risk factor in hemodialysis patients, the first step would be to assess the level of BP accurately. To manage hypertension, limiting dietary fluide intake, and individualizing dialysate sodium delivery would be the initial steps as non pharmacological measures. Therefore as a pharmacological measurement, study was conducted to determine control of blood pressure by anti hypertensive drug treatment. Material And Method: Treatment and control of hypertension was assessed retrospectively in a cohort of 100 clinically stable, adult patients undergoing hemodialysis. Frequency and duration of hemodialysis were also assessed. For quality of life, kidney disease outcomes quality initiative-survey form 1.3 health survey was used for 40 adult patients undergoing hemodialysis. Results: Hypertension was documented in patients (n=97) with complicated kidney disease (97.16%) and patients (n=85) with non-complicated kidney disease (85.66%). Hypertension was adequately controlled in only 2.83% (n=3) patients with complicated kidney disease and 14.33% patients (n=15) with non complicated kidney disease undergoing maintainanace hemodialysis. Patients with non-diabetic kidney disease had better quality of life as compared to the patients with diabetic kidney disease. Conclusion: Control of hypertension, particularly systolic hypertension, in patients undergoing hemodialysis for prolong period was inadequate, despite recognition of its prevalence and the use of antihypertensive drugs. Optimizing the use of medications and closer attention to non pharmacological interventions, may improve control of BP.
No takes yet. Share an insight, caveat, or question.
Patel et al. (2015) conducted a cohort in End Stage Renal Disease (n=100). Antihypertensive drug treatment was evaluated on Adequate control of hypertension. Control of hypertension with antihypertensive drugs was inadequate, achieved in only 2.83% of patients with complicated kidney disease and 14.33% with non-complicated kidney disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: