What question did this study set out to answer?

To assess low haemoglobin deferral rates and anaemia prevalence among prospective blood donors using routine copper sulphate screening and gender-specific WHO criteria.

January 1, 2025Advances in HematologyOpen Access

Deferrals for Low Haemoglobin and Anaemia Among First‐Time Prospective Blood Donors in Southern Ghana: Results From the BLOODSAFE Ghana—Iron and Nutritional Counselling Strategy Pilot (BLIS) Study

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Authors

CSCatherine SegbefiaUniversity of Ghana STSusan TelkeUniversity of Minnesota EOEdeghonghon OlayemiUniversity of Ghana

Discussion

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Implication

Randomized trial reveals high anaemia prevalence and low haemoglobin deferrals among prospective blood donors, highlighting barriers to maintaining a safe blood supply.

Key Points

To assess low haemoglobin deferral rates and anaemia prevalence among prospective blood donors using routine copper sulphate screening and gender-specific WHO criteria.
Conducted within an interventional pilot trial (NCT04949165) evaluating N=1213 prospective blood donors screened via the copper sulphate test over 16 months in Ghana.
Obtained full blood counts from N=325 eligible, consenting donors to determine anaemia prevalence according to WHO criteria using bias-adjusted models.
Low haemoglobin led to deferral in 6.4% (78/1213) of prospective donors, with 91% (71/78) of deferrals occurring in females and 99% (77/78) in first-time donors.
Model-based estimates showed that 61.6% of female donors (95% CrI: 53.4%–70.8%) and 19.7% of male donors (95% CrI: 11.5%–33.8%) were anaemic by WHO criteria.
Among 252 consenting donors who met haemoglobin thresholds for donation, 47% (118/252) met WHO criteria for anaemia.

Cite This Study

Segbefia et al. (2025) studied this question.

synapsesocial.com/papers/6a93f5d18e5b8037ce43eb26 https://doi.org/10.1155/ah/9971532

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Implication

Randomized trial reveals high anaemia prevalence and low haemoglobin deferrals among prospective blood donors, highlighting barriers to maintaining a safe blood supply.

Deferrals for Low Haemoglobin and Anaemia Among First‐Time Prospective Blood Donors in Southern Ghana: Results From the BLOODSAFE Ghana—Iron and Nutritional Counselling Strategy Pilot (BLIS) Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Deferrals for Low Haemoglobin and Anaemia Among First‐Time Prospective Blood Donors in Southern Ghana: Results From the BLOODSAFE Ghana—Iron and Nutritional Counselling Strategy Pilot (BLIS) Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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