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The DifSets package for GAP implements an algorithm for enumerating all difference sets in a group up to equivalence and provides access to a library of results. The algorithm functions by finding difference sums, which are potential images of difference sets in quotient groups of the original group, and searching their preimages. In this way, the search space can be dramatically decreased, and searches of groups of relatively large order (such as order 64 or order 96) can be completed.
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Dylan Peifer (2019) studied this question.
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