Key result
Deep venous thrombosis of the leg following effort, strain, or trauma is a recognized clinical entity that has been associated with fatal pulmonary embolism in historical autopsy series.
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Effort-related leg DVT warrants clinical vigilance for PE; Level 5 historical data leave open the need for prospective validation.
Chilton Crane (1952) conducted a review in Deep venous thrombosis. Effort or strain was evaluated. Deep venous thrombosis of the leg following effort, strain, or trauma is a recognized clinical entity that has been associated with fatal pulmonary embolism in historical autopsy series.
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