Intravenous Amrinone

Letters and Corrections1 October 1985Intravenous AmrinoneRICHARD A. GOLDSTEIN, M.D., GERALD V. NACCARELLI, M.D.RICHARD A. GOLDSTEIN, M.D.Search for more papers by this author, GERALD V. NACCARELLI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-4-643_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The recent editorial on intravenous amrinone by Franciosa (1) cited an article by our group (2). Dr. Franciosa implied that we saw proarrhythmic effects with the drug. We wish to correct that implication. We observed no change in inducibility of ventricular tachycardia or frequency of ventricular ectopy by Holter monitoring and concluded that the drug has little potential for inducing arrhythmias. We also found that the drug enhanced atrioventricular conduction and suggested that it could facilitate the ventricular response in patients with atrial fibrillation, an effect that is shared by the inotropic catecholamines.Several other statements in...References1. FRANCIOSA J. Intravenous amrinone: an advance or wrong step [Editorial]? Ann Intern Med. 1985;102:399-400. LinkGoogle Scholar2. NACCARELLI G, GRAY E, DOUGHERTY A, HANNA J, and GOLDSTEIN R. Amrinone: acute electrophysiologic and hemodynamic effects in patients with congestive heart failure. Am J Cardiol. 1984;54:600-4. CrossrefMedlineGoogle Scholar3. DUNKMAN W, EILENE M, and FRANCIOSA J. Adverse effects of long-term amrinone administration in congestive heart failure. Am Heart J 1983;105:861-3. CrossrefMedlineGoogle Scholar4. WILMHURST P and WEBB-PEPLOE M. Side effects of amrinone therapy. Br Heart J. 1983;49:447-51. CrossrefMedlineGoogle Scholar5. LEIER C, DALPIAZ K, and HUSS P. Amrinone therapy for congestive heart failure in outpatients with idiopathic dilated cardiomyopathy. Am J Cardiol. 1983;52:304-8. CrossrefMedlineGoogle Scholar6. KINNEY E, CARLIN B, BALLARD J, BURKS J, HALLAHAM W, and ZELIS R. Clinical experience with amrinone in patients with advanced congestive heart failure. J Clin Pharmacol. 1982;22:443-40. CrossrefGoogle Scholar1. NACCARELLI G, GRAY E, DOUGHERTY A, HANNA J, and GOLDSTEIN R. Amrinone: acute electrophysiologic and hemodynamic effects in patients with congestive heart failure. Am J Cardiol. 1984;54:600-4. CrossrefMedlineGoogle Scholar2. HERMILLER J, LEITHE M, MAGORIEN R, UNVERFERTH D, and LEIER C. Amrinone in severe congestive heart failure: another look at an intriguing new cardioactive drug. J Pharmacol Exp Ther. 1984;228:319-26. MedlineGoogle Scholar3. LEIER C, DALPIAZ K, and HUSS P. Amrinone therapy for congestive heart failure in outpatients with idiopathic dilated cardiomyopathy. Am J Cardiol. 1983;52:304-8. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RICHARD A. GOLDSTEIN, M.D.; GERALD V. NACCARELLI, M.D.Affiliations: The University of Texas Health Science Center at Houston Houston, TX 77225 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCorrection: Letter on Intravenous Amrinone 1 October 1985Volume 103, Issue 4Page: 643-644KeywordsArrhythmiaAtrial fibrillationCatecholaminesDrugsTherapeutic drug monitoringVentricular tachycardia ePublished: 1 December 2008 Issue Published: 1 October 1985 PDF downloadLoading ...