Key result
Salivary Troponin I concentrations showed a weak positive significant correlation (r=0.1, P<0.05) with serum Troponin I levels during acute myocardial infarction.
Why the study?
Does salivary Troponin I correlate with plasma Troponin I in patients with acute myocardial infarction?
Cross-Sectional (n=100)
No
Does salivary Troponin I correlate with plasma Troponin I in patients with acute myocardial infarction?
Effect estimate: r=0.1
p-value: p=<0.05
Salivary troponin I shows a weak positive correlation with serum troponin I in patients with acute myocardial infarction, suggesting limited utility as a standalone non-invasive diagnostic alternative.
Weak salivary-plasma TnI correlation warrants clinical caution; leaves open need for prospective validation before diagnostic use.
early identification is crucial for management. One analytical technique for the diagnosis of MI is evaluating plasma troponin (Tn) values. Bearing in mind the problems of blood aspiration from patients, a noninvasive practice like measuring of saliva Tn can be used as an alternative way. The present works aims to inspect variations in plasma & salivary Troponin I (TnI) measurements in AMI patients.Methods: The study involved 100 patients diagnosed as AMI by physicians. After obtaining their agreement, both salivary & plasma TnI levels was assessed by saliva & blood sampling consequently by means of; VIDUS® techniques and kits.Results: The mean age of patients was 56.5years and 79% of patients were male. There was week positive correlation between blood and serum troponin levels (r=0.1, P<0.05). The mean troponin level in serum was 8.07ng/L and troponin level in salvia was 0.16 ng/L showing a steady increase in saliva and blood during the process of AMI. There was no significant correlation of both serum & salivary TnI with increasing age or with gender differences.Conclusion: There was week positive significant correlation between S TnI & Sal TnI concentrations showing a steady increase in saliva and blood during the process of AMI.
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Al-hindi et al. (2016) conducted a cross-sectional in Acute Myocardial Infarction (n=100). Salivary Troponin I measurement vs. Serum Troponin I measurement was evaluated on Correlation between serum and salivary Troponin I levels (r=0.1, p=<0.05). Salivary Troponin I concentrations showed a weak positive significant correlation (r=0.1, P<0.05) with serum Troponin I levels during acute myocardial infarction.
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