⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

June 1, 1988Nucleosides and Nucleotides

Triaryl(Oxy)Phosphine Dibromide- A Convenient Reagent for the Preparation ofS-Arylthioinosines andN6, 5′-Disubstituted Adenosine Derivatives from Inosine

Alexander J. Bridges

View at Publisher

Ask AI

Bookmark

Share

Abstract

Inosine isopropylidene 1 reacts with triphenylphosphine/phosphite dibromide and thiophenol to give 5′-bromo-S-phenylthioinosine 5 which is a versatile precursor for 5′,N 6-disubstituted adenosine derivatives.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Alexander J. Bridges (1988) studied this question.

synapsesocial.com/papers/6a940338beaf7a0a159c4cf0 https://doi.org/10.1080/07328318808068717

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 related papers. Consider them for comparative context:

1Preparation of the enantiomeric forms of 9-(5-deoxy-.alpha.-threo-pent-4-enofuranosyl)adenine and 9-(3,5-dideoxy-.beta.-D-glycero-pent-4-enofuranosyl)adenine and in vitro antileukemic screeningIn Vitro Study · 1979 · 27 citations
2Crystal and Solution Structure of 5′-O-(Guanosine-2′-O-Phosphonomethyl)Cytidine, an Isopolar Nonisosteric Phosphonate Analog Of GpCNucleosides and Nucleotides · Mon,
3Straightforward Synthesis of Lipophilic Thymidine Glucopyranosyl Monophosphates as Models for a Drug Delivery System Across Cellular MembranesNucleosides and Nucleotides · Mon,
4The Synthesis of Geometric Variants of Rigidly-Linked Uracil-{Spacer}-Uracil and Uracil-{Spacer}-Effector Molecules Using Block Assembly MethodsNucleosides and Nucleotides · Mon,
5Intramolecular Glycosylation to Form 4-Methoxy-2,6-Dioxopyrimidine Nucleosides via O⁶,5′-CyclonucleosidesNucleosides and Nucleotides · Mon,

More from Nucleosides and Nucleotides

Random Mutagenesis Using 2-Amino-9-(2-Deoxy-β-D-Ribofuranosyl)Purine-5′-Triphosphate and the Polymerase Chain ReactionMon,
5′-Tailed Octanucleotide Primers for Cycle SequencingMon,
Oligonucleotide Conjugated to Linear and Branched High Molecular Weight Polyethylene Glycol as Substrates for RNase HMon,
Analogs of AICA- andIsoAICA Ribosides and Their Methylated Base CounterpartsMon,
d(GCGTAGC), an Equilibrium Between a Hairpin Structure and an Unusual DuplexMon,