Key result
An increase in heart rate during the recovery period of a treadmill test strongly predicted severe myocardial ischemia with a specificity of 92.56% and sensitivity of 53.33%.
Why the study?
Does heart rate response during exercise and recovery correlate with the severity of myocardial ischemia in patients with angina?
Observational (n=81)
No
Does heart rate response during exercise and recovery correlate with the severity of myocardial ischemia in patients with angina?
An increase in heart rate during the recovery period of a treadmill test, rather than a decrease, strongly correlates with severe myocardial ischemia and possible exercise-induced left ventricular dysfunction.
Hypothesis-generating for recovery heart rate in ischemia prediction; prospective validation needed before clinical adoption.
We evaluated eighty one patients complaining of angina or angina equivalent symptoms on effort. Treadmill tests were performed using Bruce protocol. All confounding factors were excluded. Severity of exercise induced myocardial ischemia was decided by clinical and electrocardiographic findings during exercise and recovery. Heart rate response during exercise and recovery was correlated with severity of myocardial ischemia. Chronotropic incompetence had low sensitivity but high specificity in diagnosing severe myocardial ischemia. Decreased magnitude of reduction in heart rate during the first minute of recovery also correlated with severe exercise induced myocardial ischemia. Combining the two parameters increased sensitivity with mild reduction in specificity. Increase, rather than decrease, in heart rate during recovery period strongly correlated with severe myocardial ischemia with possibility of exercise induced left ventricular dysfunction
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Mittal SR (2023) conducted an observational in Angina or angina equivalent symptoms (n=81). Heart rate response during exercise and recovery vs. Normal heart rate response was evaluated on Diagnosis of severe myocardial ischemia using increase in heart rate during recovery (Sensitivity 53.33%, Specificity 92.56%). An increase in heart rate during the recovery period of a treadmill test strongly predicted severe myocardial ischemia with a specificity of 92.56% and sensitivity of 53.33%.
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