Key result
HIV infection and zidovudine exposure were independently correlated with a higher prevalence of asymptomatic cardiac diastolic dysfunction (P < 0.05).
Why the study?
Is HIV infection associated with an increased prevalence of cardiac diastolic dysfunction in asymptomatic patients?
Population
114 subjects in China, comprising 84 HIV-infected patients without cardiovascular symptoms and 30…
Comparison
HIV infection vs HIV-negative control subjects
Design
Cross-sectional
Authors
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May prompt echocardiographic assessment in asymptomatic HIV patients; leaves open causality of zidovudine and need for prospective confirmation.
Cross-Sectional (n=114)
Is HIV infection associated with an increased prevalence of cardiac diastolic dysfunction in asymptomatic patients?
p-value: p=<0.05
Asymptomatic cardiac diastolic dysfunction is highly prevalent in HIV-infected individuals and is associated with both the infection itself and zidovudine exposure.
Luo et al. (2010) conducted a cross-sectional in HIV infection (n=114). HIV infection vs. HIV-negative controls was evaluated on Cardiac diastolic dysfunction (p=<0.05). HIV infection and zidovudine exposure were independently correlated with a higher prevalence of asymptomatic cardiac diastolic dysfunction (P < 0.05).
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