Key result
In acute pulmonary embolism, 48.2% and 17.1% of deaths in high and intermediate-high-risk patients occurred on the first hospital day, with substantial PE deaths also occurring after 6 days.
Why the study?
Management of acute pulmonary embolism depends on severity, but the timing of death across various risk subgroups is only partially known.
Population
1618 patients with acute pulmonary embolism confirmed by computed tomography pulmonary angiography
Comparison
Four admission mortality risk strata according to ESC criteria
Design
Registry-based cohort study
Authors
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Registry timing data in aPE risk strata should not change practice; leaves open whether stratification refines monitoring or prognosis.
Cohort (n=1,618)
In acute pulmonary embolism, PE-related mortality is prominent on the first hospitalization day for high and intermediate-high-risk patients, though a substantial proportion of deaths in these groups still occur after the first 6 days.
Obradović et al. (2023) conducted a cohort in acute pulmonary embolism (n=1,618). ESC mortality risk stratification (high and intermediate-high risk) vs. Low and intermediate-low risk groups was evaluated on PE-related and non-PE-related hospital death rates and timing. In acute pulmonary embolism, 48.2% and 17.1% of deaths in high and intermediate-high-risk patients occurred on the first hospital day, with substantial PE deaths also occurring after 6 days.
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