Key result
Among hospitalized children under 5 years with rotavirus diarrhea in Spain, G9 (50.6%) and G3 (33.0%) emerged as the predominant rotavirus genotypes.
Observational (n=656)
Yes
A major epidemiological shift occurred in Spain during 2005-2006, with rotavirus genotypes G9 and G3 emerging as the predominant causes of acute gastroenteritis in hospitalized children.
May warrant ongoing rotavirus genotype surveillance in Spain; leaves open effects on vaccine performance.
In Spain, diarrhea remains a major cause of illness among infants and young children. To determine the prevalence of rotavirus genotypes and temporal and geographic differences in strain distribution, a structured surveillance study of hospitalized children <5 years of age with diarrhea was initiated in different regions of Spain during 2005. Rotavirus was detected alone in samples from 362 (55.2%) samples and as a coinfection with other viruses in 41 samples (6.3%). Enteropathogenic bacterial agents were detected in 4.9% of samples; astrovirus and norovirus RNA was detected in 3.2% and 12.0% samples, respectively; and adenovirus antigen was detected in 1.8% samples. Including mixed infections, the most predominant G type was G9 (50.6%), followed by G3 (33.0%) and G1 (20.2%). Infection with multiple rotavirus strains was detected in >11.4% of the samples studied during 2005.
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Sánchez-Fauquier et al. (2006) conducted an observational in Acute gastroenteritis (n=656). Rotavirus infection was evaluated on Prevalence of rotavirus genotypes. Among hospitalized children under 5 years with rotavirus diarrhea in Spain, G9 (50.6%) and G3 (33.0%) emerged as the predominant rotavirus genotypes.
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