Key result
Concomitant hypertension in hospitalized patients with atrial fibrillation was associated with significantly higher rates of in-hospital mortality (5.3% vs 3.5%) and stroke (0.7% vs 0.2%) compared to those without hypertension.
Why the study?
Most literature on AF is based on Caucasian patients from the developed world, with very limited data on AF in other ethnicities.
Does concomitant hypertension worsen in-hospital mortality and stroke in hospitalized Middle Eastern Arab and South Asian patients with atrial fibrillation?
Observational (n=3,850)
No
Does concomitant hypertension worsen in-hospital mortality and stroke in hospitalized Middle Eastern Arab and South Asian patients with atrial fibrillation?
Absolute Event Rate: 5.3% vs 3.5%
p-value: p=0.007
Concomitant hypertension in Middle Eastern Arab and South Asian patients hospitalized with atrial fibrillation is associated with a higher burden of comorbidities and increased in-hospital mortality and stroke.
May warrant closer monitoring in AF inpatients with hypertension; leaves open whether BP control improves outcomes.
Background: The vast majority of literature on atrial fibrillation (AF) is based on studies from the developed world that mainly includes Caucasian patients. Data on AF in other ethnicities is very limited. The aim of this hospital-based study is to evaluate the effect of concomitant hypertension (HTN) on the characteristics and outcomes of Middle Eastern Arab and South Asian patients with AF in the state of Qatar. Materials and Methods and Results: During the 20-year period, 3850 AF patients were hospitalized; 1483 (38.5%) had HTN, and 2367 (61.5%) without HTN. Patients with HTN were 11 years older, compared to non-HTN patients, and had a significantly higher prevalence of diabetes mellitus, chronic kidney disease, and dyslipidemia, compared to non-HTN patients. Furthermore, underlying coronary artery disease and heart failure were significantly more common but not valvular and rheumatic heart diseases which were more common in those without HTN. The rates of in-hospital mortality and stroke were significantly higher in the presence of HTN (5.3% versus 3.5%, and 0.7% versus 0.2% respectively, P = 0.001), compared to non-HTN patients. Conclusions: HTN is significantly associated with more comorbidities and worse clinical outcomes when it coexists with AF in hospitalized Middle Eastern Arab and South Asian patients.
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A 2021 study conducted an observational in Atrial Fibrillation (n=3,850). Hypertension vs. Without hypertension was evaluated on In-hospital mortality (p=0.007). Concomitant hypertension in hospitalized patients with atrial fibrillation was associated with significantly higher rates of in-hospital mortality (5.3% vs 3.5%) and stroke (0.7% vs 0.2%) compared to those without hypertension.
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