Key result
Atrial fibrillation in ischemic stroke patients was associated with a higher risk of parenchymal hematoma compared to those without AF (29% vs 5%; OR 6.90, 95% CI 1.57-30.25).
Why the study?
Does the presence of atrial fibrillation worsen clinical and imaging outcomes following ischemic stroke?
Population
101 patients with ischemic stroke enrolled in the Echoplanar Imaging Thrombolytic Evaluation Trial…
Comparison
Presence of atrial fibrillation (AF) vs Absence of atrial fibrillation
Design
Cohort
Authors
Loading...
AF may heighten parenchymal hematoma risk after ischemic stroke; leaves open causal mechanisms and optimal management.
Observational (n=101)
Does the presence of atrial fibrillation worsen clinical and imaging outcomes following ischemic stroke?
Odds Ratio: 6.9 (95% CI 1.57–30.25)
Absolute Event Rate: 29% vs 5%
p-value: p=0.002
Patients with atrial fibrillation have worse clinical and imaging outcomes following ischemic stroke, driven by greater volumes of severely hypoperfused tissue leading to larger infarcts and higher risk of hemorrhagic transformation.
Tu et al. (2010) conducted an observational in Ischemic stroke (n=101). Atrial fibrillation vs. No atrial fibrillation was evaluated on Parenchymal hematoma (OR 6.90, 95% CI 1.57-30.25, p=0.002). Atrial fibrillation in ischemic stroke patients was associated with a higher risk of parenchymal hematoma compared to those without AF (29% vs 5%; OR 6.90, 95% CI 1.57-30.25).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: