Key result
Bibliometric analysis of 1,516 articles from 2012 to 2022 showed significant growth in research on lncRNAs in angiogenesis-related diseases, with China leading in publication volume.
Why the study?
Long noncoding RNAs play key roles in angiogenesis-related diseases, but global research trends, hotspots, and future research directions had not been characterized.
Research on lncRNAs in angiogenesis-related diseases has grown significantly, with vascular remodeling and dysfunction emerging as key future research directions.
Maps lncRNA-angiogenesis trends; leaves open experimental validation before clinical translation.
OBJECTIVES: Long noncoding RNAs (lncRNA) play important roles in the pathological processes of angiogenesis-related diseases such as cancer and diabetic retinopathy. This study aims to identify global research trends and hotspots in the field of lncRNAs in angiogenesis-related diseases and to explore future research directions. METHODS: Relevant literature published between 2012 and 2022 was retrieved from the Web of Science Core Collection (WoSCC). A total of 1 516 articles on lncRNAs and angiogenesis-related diseases were included for bibliometric analysis. CiteSpace and VOSviewer were used to analyze publication countries, institutions, journals, authors, co-cited references, and key words. RESULTS: was the most frequently cited journal. The latest terms of burst key words were vascular remodeling, dysfunction, heart, target, suppress, and pulmonary arterial hypertension. CONCLUSIONS: From 2012 to 2022, research on lncRNAs in angiogenesis-related diseases has grown significantly. China leads in publication volume, while the United States holds the most academic influence. Emerging research hotspots such as vascular remodeling and dysfunction point to key directions for future research.
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Wang et al. (2024) studied Angiogenesis-related diseases (n=1,516). lncRNA research was evaluated on Global research trends and hotspots. Bibliometric analysis of 1,516 articles from 2012 to 2022 showed significant growth in research on lncRNAs in angiogenesis-related diseases, with China leading in publication volume.
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