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Basal-cell carcinoma with perineural invasion is a rare occurrence. Ten patients with this phenomenon are described. Review of our cases and cases in the literature indicates that perineural spread of basal-cell carcinoma is most common in men with recurrent tumors. The horizontally cut frozen sections that are utilized in Mohs surgery maximize the chances of discovering basal-cell carcinoma with undiagnosed involvement.
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Hanke et al. (1983) studied this question.
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