What question did this study set out to answer?

To characterize pain in patients with severe haemophilia and investigate how pain contributes to self-perceived functional limitations.

February 13, 2006Haemophilia

Pain and functional limitations in patients with severe haemophilia

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To characterize pain in patients with severe haemophilia and investigate how pain contributes to self-perceived functional limitations.
Surveyed 78 adult patients (aged 18–70) with severe haemophilia using questionnaires evaluating pain characteristics and self-perceived functional abilities.
Retrieved radiological joint damage data via Pettersson scores for a subgroup of 28 younger patients receiving prophylaxis.
More than two-thirds of patients had multiple painful joints (most commonly the ankle, n=43), but only 36% of patients experiencing pain reported using analgesics.
Pain parameters accounted for 3% to 22% of the variance in self-perceived functional abilities after adjusting for age and treatment modality.
Radiological joint damage assessed by Pettersson scores showed no significant correlation with pain parameters in the examined subgroup (n=28).

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Implication

Observational study reveals joint pain significantly predicts functional limitations in severe haemophilia, suggesting better pain management may improve physical function.

Cite This Study

Genderen et al. (2006) studied this question.

synapsesocial.com/papers/6a94140f582b3c5feaf641e1 https://doi.org/10.1111/j.1365-2516.2006.01203.x

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Implication

Observational study reveals joint pain significantly predicts functional limitations in severe haemophilia, suggesting better pain management may improve physical function.

Pain and functional limitations in patients with severe haemophilia

Key Points

Discussion

Implication

Cite This Study

Pain and functional limitations in patients with severe haemophilia

Key Points

Discussion

Implication

Cite This Study

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