Male hypogonadism is characterised by sexual dysfunction, loss of muscle bulk, central obesity, fatigue, mood and sleep disturbances, osteoporosis, and anaemia. Although these features are associated with low serum testosterone, not all men with low serum testosterone are definitively hypogonadal, and there is a large symptom overlap with obesity and non-endocrine illness. Importantly, testosterone replacement may not be appropriate for …
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Gan et al. (2012) studied this question.
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