Key result
The study investigated the proliferation and transformation of lymphoid cells into hemopoietic precursors in sublethally irradiated dogs using serial autoradiography with H3-thymidine.
Population
Normal and sublethally irradiated dogs
Design
Preclinical
Authors
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Animal data on post-radiation lymphoid transformation remain hypothesis-generating; leaves open translation to human hematopoietic recovery.
Keiser et al. (1966) studied Normal and sublethally irradiated dogs. Sublethal irradiation and H3-thymidine injection vs. Normal dogs was evaluated on Proliferation of lymphoid cells and transformation into hemopoietic precursors. The study investigated the proliferation and transformation of lymphoid cells into hemopoietic precursors in sublethally irradiated dogs using serial autoradiography with H3-thymidine.
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