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All articles of this category Different strategies for the fluorescence labeling of nucleosides and oligonucleotides and techniques for their detection are discussed. Pre- and post-synthetic routes as well as automated solid phase-based syntheses and enzymatic methods are compared. Tailor-made chemical syntheses are presented that meet the requirements of a broad spectrum of applications for oligonucleotides as probes. fluorescent oligonucleotides - automated solid-phase synthesis - modified nucleosides - fluorescence spectroscopy - DNA
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Wojczewski et al. (1999) studied this question.
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