Key result
Fibrillin-1 mutations and its derived hormone asprosin contribute to adipose tissue dysfunction and metabolic syndrome through impaired adipogenesis and altered glucose and insulin signaling.
Why the study?
Understanding the dynamic role of fibrillin-1 in adipose tissue and circulating asprosin can provide novel mechanistic insights into how fibrillin-1 contributes to metabolic syndrome.
Design
Review
Authors
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Does not support practice changes in metabolic syndrome; leaves open targeted research on adipose signaling pathways.
Understanding the roles of fibrillin-1 and asprosin in adipose tissue and metabolism may provide novel mechanistic insights and potential management strategies for metabolic syndrome.
Muthu et al. (2020) conducted a review in Metabolic disorders. Fibrillin-1 and asprosin was evaluated. Fibrillin-1 mutations and its derived hormone asprosin contribute to adipose tissue dysfunction and metabolic syndrome through impaired adipogenesis and altered glucose and insulin signaling.
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