Key result
Predictors of recurrence in retroperitoneal sarcoma include histological subtype, completeness of resection, and hospital case volume, with resectability being the most significant predictor of outcome.
Resectability is the most significant predictor of outcome in recurrent retroperitoneal sarcoma.
Resectability may aid prognosis in retroperitoneal sarcoma; leaves open prospective validation of subtype and volume effects.
Approximately 15% of soft tissue sarcomas are retroperitoneal. The occult location and anatomic complexity results in local recurrences in the majority of patients. Predictors of recurrence include histological subtype, completeness of resection, and the hospital case volume. The most significant predictor of outcome following local recurrence is the resectability of the recurrent disease. An understanding of the implication of tumor biology on outcomes is essential in determining optimal management for patients with recurrent retroperitoneal sarcoma.
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Gyorki et al. (2013) conducted a review in Recurrent retroperitoneal sarcoma. Predictors of recurrence in retroperitoneal sarcoma include histological subtype, completeness of resection, and hospital case volume, with resectability being the most significant predictor of outcome.
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