Growth and skeletal maturation in congenital adrenal hyperplasia. Review of 20 cases.

Growth and skeletal maturation in congenital adrenal hyperplasia: review of 20 cases. In 20 children with the salt-losing variety of congenital adrenal hyperplasia there was a significant degree of stunting and their skeletal maturation was delayed. 14 of the children were treated in the first year of life with long-acting steroid preparations and 13 of this group achieved normal height velocities during this period. Treatment thereafter was with prednisone and 9-ac-fludrocortisone, and it is concluded that the growth retardation of the children was due either to a specific effect of these drugs, or to drug overdosage.