A Sequential Space-Time Cluster Analysis of Cancer Mortality in the United States: Etiologic Implications

Burbank, F. (Epidemiology Branch, National Cancer Institute, NIH, Bethesda, Md. 20014). A sequential space-time cluster analysis of cancer mortality in the United States: Etiologic implications. Am J Epidemiol 95: 393–417, 1972.—A sequential geographic cluster and time trend analysis of United States cancer mortality for whites, 1950–1967, suggests that dissimilar neoplasms may be caused by the same carcinogen. Eleven carcinogens are postulated. Some carcinogens coincide with known agents; several new carcinogens are suggested.