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To synthesize and characterize biocompatible, hollow polymeric spheres from green tea polyphenols for controlled delivery applications.

Biocompatible, Functional Spheres Based on Oxidative Coupling Assembly of Green Tea Polyphenols

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To synthesize and characterize biocompatible, hollow polymeric spheres from green tea polyphenols for controlled delivery applications.
Assembled green tea polyphenols in aqueous media via copper ion (Cu2+) and temperature-mediated oxidative coupling.
Assessed sphere morphology, luminescence, and environmental responsiveness across acidic, alkaline, and glutathione (GSH) conditions.
Synthesized green luminescent, monodisperse, smooth, porous, and hollow polymeric spheres.
Observed stability in acidic conditions alongside selective degradation in the presence of glutathione and alkaline environments, enabling responsive cargo release.

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Experimental study demonstrates responsive hollow polyphenol spheres in water, highlighting potential for controlled therapeutic delivery.

Chen et al. (2013) studied this question.

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Experimental study demonstrates responsive hollow polyphenol spheres in water, highlighting potential for controlled therapeutic delivery.